[Epidemiological and clinical profile of skin damages in black African patients on chronic hemodialysis].

Titre[Epidemiological and clinical profile of skin damages in black African patients on chronic hemodialysis].
Publication TypeJournal Article
Year of Publication2016
AuthorsKouotou EArmand, Folefack FKaze, Tatsa JTameyi, Sieleunou I, Njingang JRichie Nan, Ashuntantang G, Bissek A-CZoung-Kany
JournalPan Afr Med J
Date Published2016
Mots-clésAdult, African Continental Ancestry Group, Age Factors, Aged, Cameroon, Cross-Sectional Studies, Female, Humans, Kidney Failure, Chronic, Male, Middle Aged, Renal Dialysis, Sex Factors, Skin Diseases

INTRODUCTION: Dermatologic manifestations are common among patients on chronic hemodialysis and may represent systemic involvement. Our study aims to determine the epidemiological and clinical profile of skin damages in black patients living in Yaounde, Cameroon.METHODS: We conducted a cross sectional study including all patients receiving chronic haemodialysis treatment for at least 3 months in two hemodialysis centers in Yaounde from February to May 2014. Patients underwent an interview and a dermatological examination. Chi-squared tests and Student's t-test (or equivalents) were used for statistical analysis, with significance level at p <0.05.RESULTS: A total of 112 patients (78 (69.9%) men) with an average age of 48.6 ± 13 years and a mean duration of dialysis of 46,3 ± 37 months were included in the study. Skin lesions were present in 94 (83.9%) patients. Xerosis (63.3%), pruritus (37.5%), melanoderma (34.8%), acne (12.5%) and half and half nails (10.7%) were the most common dermatologic manifestations. Xerosis was associated with anuria (p = 0.0001) and advanced age (p = 0.032); melanoderma was associated with anuria (p = 0.042) and time spent on dialysis (p = 0.027) while half and half nails were associated with young age (p = 0.018) and biweekly dialysis (p = 0.01 ).CONCLUSION: Skin damages are frequent and dominated by xerosis, pruritus and melanoderma in patients on chronic hemodialysis living in Yaounde. Biweekly dialysis, advanced age, anuria and time spent on dialysis were associated factors.

Alternate JournalPan Afr Med J
PubMed ID28292104
PubMed Central IDPMC5326034